China (Mainland)
BMS-852927 CAS NO.1256918-39-4
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- Product Details
Keywords
- 1256918-39-4
- BMS-852927
- LXRβ
Quick Details
- ProName: BMS-852927
- CasNo: 1256918-39-4
- Molecular Formula: C20H12N2O3S
- Appearance: white to off-white solid
- Application: BMS-852927 is an LXRβ-selective ago...
- ProductionCapacity: Metric Ton/Day
- Purity: 99% min
- LimitNum: 0 Metric Ton
Superiority
BMS-852927 is an LXRβ-selective agonist with 20% LXRα and 88% LXRβ activity compared to a full pan agonist in transactivation assays. BMS-852927 is potent, with an EC50=9 nM and 26% activity in an in vitro human whole-blood endogenous target gene activation assay (WBA). BMS-852927 has similar binding affinity to LXRα and LXRβ (19 and 12 nM, respectively)[1].